Tympanogen, Inc. develops innovative ear, nose, and throat devices based on our proprietary gel technology. Our lead product, Perf-Fix, will transform traditional tympanoplasty procedures into a quick office visit.

Perf-Fix can be applied in an office setting within 10 minutes, without general anesthesia or margin freshening. This gel patch encourages regeneration of the full tympanic membrane structure at the same high success rates of traditional tympanoplasty.

Perf-Fix is still in development, and is not yet for sale.


Tympanogen was founded in 2014 by a dynamic and energetic team of engineers and physicians dedicated to simplifying medical procedures and reducing healthcare costs. The company operates out of the VA Bio+Tech Park in Richmond, VA.

Elaine Horn-Ranney, PhD

Co-Founder & Chief Executive Officer

Elaine Horn-Ranney,PhD

Dr. Horn-Ranney has led the Tympanogen team to win national and international accolades for Tympanogen's disruptive eardrum repair technology and directs research projects aboard the International Space Station. She possesses a robust knowledge of biomaterials and synthesizing materials for tissue engineering and regenerative medicine applications, with a specialized focus on translating laboratory research into clinical products. Dr. Horn-Ranney received both her BSE and PhD in Biomedical Engineering from Tulane University, and is passionate about improving healthcare through novel devices and simplified procedures. She serves on multiple boards (Virginia Biotechnology Association, Industrial Advisory Board for ODU Department of Electrical Engineering, Ignition Center in Williamsburg), reviews grants for the National Institutes of Health, and is active in the entrepreneurial community of Hampton Roads.

Sithara Nair, PhD

Senior Scientist

Sithara Nair, PhD

Dr. Nair is synthetic chemistry expert who designs and evaluates polymers for specialized clinical applications. She has deep expertise in developing novel antimicrobial coatings and characterizing both bulk materials and polymers, as well as optimizing reagent production outcomes and implementing quality control practices. She completed her postdoctoral training in Dr. Kenneth Wynne’s laboratory at Virginia Commonwealth University (VCU) and an internship with Pfizer. Dr. Nair received her BS in Biotechnology and Biochemical Engineering from Kerala University, and both her MS and PhD in Chemical Engineering from VCU.


Parastoo Khoshakhlagh, PhD

  • Co-Founder
  • Researcher at Harvard Medical School
Parastoo Khoshakhlagh, PhD

Dr. Khoshakhlagh has over 10 years experience in the development, characterization, and evaluation of biomaterials in animal and cellular models. Her regenerative medicine expertise ranges from designing novel tissue constructs to formulating novel bioglass compositions to guiding stem cell differentiation. She completed a postdoctoral fellowship in Dr. Ali Khademhosseini’s laboratory at Harvard-MIT Department of Science and Technology, and is currently a postdoctoral fellow in Dr. George Church’s laboratory at Harvard Medical School. Dr. Khoshakhlagh received her BS in Materials Science from Iran University of Science and Technology, her MS in Biomedical Engineering from Amirkabir University of Technology, and her PhD in Biomedical Engineering from Tulane University.

Jesse Ranney, MD

  • Co-Founder
  • Pediatric Hospitalist for Children's Specialty Group
Jesse Ranney, MD

Dr. Ranney is a board-certified pediatric hospitalist at Sentara Williamsburg Regional Hospital and Children's Hospital of the King's Daughters. He actively identifies clinical issues that can be resolved with material therapies while guiding product development toward a physician-friendly format. He participates in multiple committees in both hospitals to improve and implement protocols. Dr. Ranney also hosts seminars for his staff to increase awareness of the latest research and patient-care guidelines. He received his BS in Biomedical Engineering from Tulane University, his MD from Louisiana State University, and completed his pediatrics residency training at Eastern Virginia Medical School (EVMS).

Barry Strasnick, MD, FACS

  • Chairman of the Department of Otolaryngology
  • Eastern Virginia Medical School
Barry Strasnick, MD

Dr. Strasnick is the chairman of the EVMS Department of Otolaryngology and the director of the EVMS Hearing & Balance Center. He previously co-founded and served as the Chief Medical Officer of Tympany, a hearing device company, which was successfully acquired by Ototronix. Dr. Strasnick is a renowned neurotologist and thought leader in pediatric hearing tests, having published two books, 18 book chapters, and nearly 80 articles in peer-reviewed journals. He attended Baylor College of Medicine and UCLA School of Medicine for residency and completed his Otology/Neurotology fellowship at the Otology Group in Nashville. He serves on multiple boards and committees in his professional organizations.


CIT GAP Funds invests in Tympanogen

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Richmond Times-Dispatch features Tympanogen in its Startup Spotlight

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Tympanogen CEO featured on NASA's "What's on Board" program (video)

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Tulane highlights Tympanogen project launched on SpaceX rocket

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